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Overexpression of manganese or copper–zinc superoxide dismutase inhibits breast cancer growth

✍ Scribed by Christine J. Weydert; Trent A. Waugh; Justine M. Ritchie; Kanchan S. Iyer; Jenna L. Smith; Ling Li; Douglas R. Spitz; Larry W. Oberley

Book ID
113629961
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
518 KB
Volume
41
Category
Article
ISSN
0891-5849

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NIH/3T3 mouse fibroblasts were transfected with the cDNA for manganese superoxide dismutase (MnSOD), and two clones overexpressing MnSOD activity were subsequently characterized by comparison with parental and control plasmidtransfected cells. One clone with a 1.8-fold increase in MnSOD activity had