๐”– Bobbio Scriptorium
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Mammalian artificial chromosomes

โœ Scribed by William Brown; Raoul Heller; Marie-Louise Loupart; Ming-Hong Shen; Aarti Chand


Book ID
117655160
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
646 KB
Volume
6
Category
Article
ISSN
0959-437X

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A mammalian artificial chromosome (MAC) may be assembled through the juxtapposition of three kinds of DNA elements: a centromere, several DNA replication origins, and two telomeric repeats. The resulting structure should be able to carry and express one or more selected genes (transgenes), introduce