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Mammalian artificial chromosomes

โœ Scribed by Sinclair, Meeghan


Book ID
109829162
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
248 KB
Volume
18
Category
Article
ISSN
1087-0156

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A mammalian artificial chromosome (MAC) may be assembled through the juxtapposition of three kinds of DNA elements: a centromere, several DNA replication origins, and two telomeric repeats. The resulting structure should be able to carry and express one or more selected genes (transgenes), introduce