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Magnetic circular dichroism study of the binding of netropsin and distamycin-A with DNA

โœ Scribed by C. Zimmer; C. Marck; C. Schneider; D. Thiele; G. Luck; W. Guschlbauer


Book ID
115747399
Publisher
Elsevier Science
Year
1980
Weight
778 KB
Volume
607
Category
Article
ISSN
0005-2787

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Accessibility of the minor groove of DNA
โœ A. F. Melnikova; A. S. Zasedatelev; A. M. Kolchinsky; G. V. Gursky; A. L. Zhuze; ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› Springer ๐ŸŒ English โš– 380 KB

The interaction of the antibiotics distamycin A, distamycin analogue and netropsin with chromatin of calf thymus has been studied by circular dichroism measurements and by gel filtration. The minor groove of DNA in chromatin is accessible by 83-89% to the binding of these antibiotics as compared wit