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Macrophage activation syndrome in juvenile idiopathic arthritis

✍ Scribed by Elisabetta Cortis; Antonella Insalaco

Book ID: 114814911
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 77 KB
Volume: 95
Category: Article
ISSN: 0803-5253
DOI: 10.1111/j.1651-2227.2006.tb02414.x

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## Abstract The aberrant induction of proinflammatory cytokines is considered to be crucial in the pathogenesis of systemic juvenile idiopathic arthritis and adult‐onset Still's disease. Interleukin‐18 (IL‐18) in particular has been reported to be a candidate for the key cytokine in both diseases;