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Macrophage activation syndrome in 13 children with systemic-onset juvenile idiopathic arthritis

✍ Scribed by Hua-Song Zeng; Xiao-Yan Xiong; Yan-Dan Wei; Hong-Wei Wang; Xiao-Ping Luo

Book ID
107659759
Publisher
SP Children’s Hospital, Zhejiang University School of Medicine
Year
2008
Tongue
English
Weight
124 KB
Volume
4
Category
Article
ISSN
1708-8569

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## Abstract The aberrant induction of proinflammatory cytokines is considered to be crucial in the pathogenesis of systemic juvenile idiopathic arthritis and adult‐onset Still's disease. Interleukin‐18 (IL‐18) in particular has been reported to be a candidate for the key cytokine in both diseases;