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Large pericardial effusion requiring pericardiocentesis as cardinal sign of macrophage activation syndrome in systemic onset-juvenile idiopathic arthritis

✍ Scribed by Donato Rigante; Gabriella De Rosa; Barbara Bertoni; Valentina Ansuini; Manuela Pardeo; Ilaria La Torraca; Stefania Gaspari; Achille Stabile

Publisher
Springer
Year
2006
Tongue
English
Weight
261 KB
Volume
27
Category
Article
ISSN
0172-8172

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✍ Jack Bleesing; Anne Prada; David M. Siegel; Joyce Villanueva; Judyann Olson; Nor 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 275 KB 👁 2 views

## Abstract ## Objective Macrophage activation syndrome is characterized by an overwhelming inflammatory reaction driven by excessive expansion of T cells and hemophagocytic macrophages. Levels of soluble interleukin‐2 receptor α (sIL‐2Rα) and soluble CD163 (sCD163) may reflect the degree of activ