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Macromolecular Complexes : 3D Cryo Transmission Electron Microscopy Studies

✍ Scribed by Hans Hebert

Publisher
Wiley (John Wiley & Sons)
Year
2007
Weight
819 KB
Volume
9
Category
Article
ISSN
1439-4243

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✦ Synopsis

CryoEM can be divided into three different sub-disciplines: electron crystallography where the macromolecules are arranged periodically into thin crystals, single particle cryoEM of randomly oriented isolated macromolecular assemblies and electron tomography of vitreous specimens containing objects in situ or in isolated form but being reconstructed individually. These methods provide a comprehensive, complementary approach of transmission electron microscopy (TEM) for studies of biological structure reaching from the atomic to the cellular level.

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