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M6P/IGF2R tumor suppressor gene mutated in hepatocellular carcinomas in Japan

โœ Scribed by Yoshihiko Oka; Robert A. Waterland; J.Keith Killian; Catherine M. Nolan; Hong-Seok Jang; Keiji Tohara; Seigo Sakaguchi; Tsuneyoshi Yao; Akinori Iwashita; Yutaka Yata; Terumi Takahara; Shin-ichiro Sato; Kazuyuki Suzuki; Tomoyuki Masuda; Randy L. Jirtle

Book ID
111721820
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
370 KB
Volume
35
Category
Article
ISSN
0270-9139

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The mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) suppresses cell growth through binding to the insulin-like growth factor 2 (IGF2) and latent complex of the transforming growth factor-โค (TGF-โค). Recently, it was reported in the United States that loss of heterozygosity (LOH)