Cathepsins and compartmentalization in a
✍
Richard J Riese; Harold A Chapman
📂
Article
📅
2000
🏛
Elsevier Science
🌐
English
⚖ 93 KB
Intracellular trafficking and cell surface expression of MHC class II molecules is a tightly regulated process and is to a large extent, determined by the fate of the class II chaperone, the invariant chain. Inhibition of endosomal proteases critical to invariant chain proteolysis reveals marked shu