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Cathepsin G: Roles in antigen presentation and beyond

✍ Scribed by Timo Burster; Henriette Macmillan; Tieying Hou; Bernhard O. Boehm; Elizabeth D. Mellins

Book ID
116757582
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
428 KB
Volume
47
Category
Article
ISSN
0161-5890

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Intracellular trafficking and cell surface expression of MHC class II molecules is a tightly regulated process and is to a large extent, determined by the fate of the class II chaperone, the invariant chain. Inhibition of endosomal proteases critical to invariant chain proteolysis reveals marked shu