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Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

✍ Scribed by Zhang, Hua; Chua, Kevin S; Guimond, Martin; Kapoor, Veena; Brown, Margaret V; Fleisher, Thomas A; Long, Lauren M.; Bernstein, Donna; Hill, Brenna J; Douek, Daniel C

Book ID
109932769
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
460 KB
Volume
11
Category
Article
ISSN
1078-8956

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## Abstract Immunosuppressants are powerful drugs, capable of triggering severe adverse effects. Hence, there is tremendous interest in replacing them with less‐toxic agents. Adoptive therapy with CD25^+^CD4^+^ T regulatory cells (Tregs) holds promise as an alternative to immunosuppressants. Tregs