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Lymphocyte concanavalin A capping in hereditary cerebral haemorrhage with amyloidosis — Dutch type

✍ Scribed by J. Haan; R. T. Demmers; O. J. S. Buruma; R. A. C. Roos


Publisher
Springer
Year
1990
Tongue
English
Weight
251 KB
Volume
237
Category
Article
ISSN
0340-5354

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✍ Kazuchika Nishitsuji; Takami Tomiyama; Kenichi Ishibashi; Fuyuki Kametani; Kazuh 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 284 KB

## Abstract Hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA‐D), is an autosomal dominant disorder caused by the Dutch mutation (E693Q) in the β‐amyloid precursor protein. This mutation produces an aberrant amyloid β (Aβ) species (AβE22Q) and causes severe meningocortical vascular