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LRRK2 R1398H polymorphism is associated with decreased risk of Parkinson’s disease in a Han Chinese population

✍ Scribed by Ling Chen; Sile Zhang; Yanmei Liu; Hua Hong; Hongxuan Wang; Yifan Zheng; Hongyan Zhou; Jie Chen; Wenbiao Xian; Yuemei He; Jinru Li; Zhuolin Liu; Zhong Pei; Jinsheng Zeng

Book ID
116820884
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
93 KB
Volume
17
Category
Article
ISSN
1353-8020

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LRRK2 R1628P variant is a risk factor of
LRRK2 R1628P variant is a risk factor of Parkinson's disease among Han-Chinese from mainland China
✍ Zijuan Zhang; Jean-Marc Burgunder; Xingkai An; Yan Wu; Wenjun Chen; Jinhong Zhan 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 66 KB

## Abstract Mutations in __LRRK2__, the gene that encodes leucine‐rich repeat kinase 2 (LRRK2), are associated with autosomal dominant and sporadic forms of Parkinson's disease (PD) and are the most common genetic causes of PD. Recently, a R1628P variant has been reported as a risk factor for PD in