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LRRK2 G2385R and LRRK2 R1628P increase risk of Parkinson's disease in a Han Chinese population from Southern Mainland China

✍ Scribed by Fu, Xiaoli; Zheng, Yifan; Hong, Hua; He, Yuemei; Zhou, Shencun; Guo, Caifeng; Liu, Yanmei; Xian, Wenbiao; Zeng, Jinsheng; Li, Jinru; Liu, Zhuolin; Chen, Ling; Pei, Zhong

Book ID
122725534
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
95 KB
Volume
19
Category
Article
ISSN
1353-8020

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## Abstract Mutations in __LRRK2__, the gene that encodes leucine‐rich repeat kinase 2 (LRRK2), are associated with autosomal dominant and sporadic forms of Parkinson's disease (PD) and are the most common genetic causes of PD. Recently, a R1628P variant has been reported as a risk factor for PD in