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LRRK2 mutation analysis in Parkinson disease families with evidence of linkage to PARK8

โœ Scribed by Nichols, W. C.; Elsaesser, V. E.; Pankratz, N.; Pauciulo, M. W.; Marek, D. K.; Halter, C. A.; Rudolph, A.; Shults, C. W.; Foroud, T.

Book ID
118234216
Publisher
Lippincott Williams and Wilkins
Year
2007
Tongue
English
Weight
721 KB
Volume
69
Category
Article
ISSN
0028-3878

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To date, molecular genetic analyses have identified over 500 distinct DNA variants in five disease genes associated with familial Parkinson disease; ฮฑ-__synuclein__ (__SNCA__), __parkin__ (__PARK2__), __PTEN-induced putative kinase 1__ (__PINK1__), __DJ-1__ (__PARK7__), and __Leucine-rich repeat kin