## Abstract The __LRRK2__ gene is a key player in Parkinson's disease (PD), however prevalence and pathogenicity of __LRRK2__ variants remain to be investigated in ethnically diverse populations. Herein, we performed comprehensive sequencing of the __LRRK2__ gene in 92 Tunisian probands with famili
✦ LIBER ✦
Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease
✍ Scribed by Di Fonzo, Alessio; Tassorelli, Cristina; De Mari, Michele; Chien, Hsin F; Ferreira, Joaquim; Rohé, Christan F; Riboldazzi, Giulio; Antonini, Angelo; Albani, Gianni; Mauro, Alessandro
- Book ID
- 110026543
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 310 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1018-4813
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## Abstract Parkinson's disease (PD) is typically a sporadic illness, but the past decade has witnessed the identification of mutations responsible for multiple familial forms of the disease. The proposed functions of some of these genes (e.g., E3 ubiquitin ligase, redox‐dependent chaperone) have l