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LRRK2 gene G2019S mutation and SNPs [haplotypes] in subtypes of Parkinson's disease

✍ Scribed by Biswanath Patra; Azemat J. Parsian; Brad A. Racette; Jing Hua Zhao; Joel S. Perlmutter; Abbas Parsian

Book ID
116820539
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
170 KB
Volume
15
Category
Article
ISSN
1353-8020

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## Abstract Among mutations associated with autosomal dominant and sporadic Parkinson's disease (PD) the G2019S substitution in the leucine‐rich repeat kinase 2 (LRRK2) gene is the most frequently identified. To estimate its frequency in Russia, we analyzed 208 patients with PD from the Northwester