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Low-density lipoprotein receptor-related protein-1 (LRP-1) expression in a rat model of oxygen-induced retinal neovascularization

✍ Scribed by María C. Sánchez; Pablo F. Barcelona; Jose D. Luna; Susana G. Ortiz; Patricio C. Juarez; Clelia M. Riera; Gustavo A. Chiabrando

Book ID
116456525
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
697 KB
Volume
83
Category
Article
ISSN
0014-4835

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## Abstract Low‐density lipoprotein receptor‐related protein 1 (LRP1) is an endocytic receptor, which binds and internalizes diverse ligands such as activated α~2~‐macroglobulin (α~2~M\*). LRP1 promotes intracellular signaling, which downstream mediates cellular proliferation and migration of diffe