Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1
✍ Scribed by Matthew J. Bown; Gregory T. Jones; Seamus C. Harrison; Benjamin J. Wright; Suzannah Bumpstead; Annette F. Baas; Solveig Gretarsdottir; Stephen A. Badger; Declan T. Bradley; Kevin Burnand; Anne H. Child; Rachel E. Clough; Gillian Cockerill; Hany Hafez; D. Julian A. Scott; Simon Futers; Anne Johnson; Soroush Sohrabi; Alberto Smith; Matthew M. Thompson; Frank M. van Bockxmeer; Matthew Waltham; Stefan E. Matthiasson; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Jan D. Blankensteijn; Joep A.W. Teijink; Cisca Wijmenga; Jacqueline de Graaf; Lambertus A. Kiemeney; Themistocles L. Assimes; Ruth McPherson; Lasse Folkersen; Anders Franco-Cereceda; Jutta Palmen; Andrew J. Smith; Nicolas Sylvius; John B. Wild; Mette Refstrup; Sarah Edkins; Rhian Gwilliam; Sarah E. Hunt; Simon Potter; Jes S. Lindholt; Ruth Frikke-Schmidt; Anne Tybjærg-Hansen; Anne E. Hughes; Jonathan Golledge; Paul E. Norman; Andre van Rij; Janet T. Powell; Per Eriksson; Kari Stefansson; John R. Thompson; Steve E. Humphries; Robert D. Sayers; Panos Deloukas; Nilesh J. Samani
- Book ID
- 113423118
- Publisher
- American Society of Human Genetics
- Year
- 2011
- Tongue
- English
- Weight
- 484 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0002-9297
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## Abstract The low‐density lipoprotein receptor‐related protein‐1 (LRP‐1) is a multifunctional receptor that undergoes constitutive endocytosis and recycling. To identify LRP‐1 in lipid rafts, we biotin‐labeled cells using a membrane‐impermeable reagent and prepared Triton X‐100 fractions. Raft‐as