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Loss of X chromosome in childhood acute lymphoblastic leukemia

✍ Scribed by Mirjam Riesch; Felix K Niggli; Kurt Leibundgut; Ueli Caflisch; David R Betts

Book ID: 114134982
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 45 KB
Volume: 125
Category: Article
ISSN: 0165-4608
DOI: 10.1016/s0165-4608(00)00354-x

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## Background: A cytogenetic study of 75 consecutive children with all revealed a normal karyotype, a low hyperdiploid karyotype (including 47-50 chromosomes), and a high hyperdiploid karyotype (including > 50 chromosomes) in 10, 12, and 33 patients, respectively. an acquired extra x-chromosome was