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Translocation between chromosomes 1 and 9 in childhood acute lymphoblastic leukemia

✍ Scribed by Kazuma Ohyashiki; Mirjana Koc̆ova; Junko H. Ohyashiki; Daniel H. Ryan; Jacob M. Rowe; Avery A. Sandberg

Book ID
119103312
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
327 KB
Volume
21
Category
Article
ISSN
0165-4608

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✍ Leonid V. Filatov; Frederick G. Behm; Ching-Hon Pui; David R. Head; James R. Dow 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 399 KB

The t(1;19)(q23;p13) or its derivative encodes an UA-PBXI fusion transcript and protein that has been shown to have important prognostic and therapeutic implications in patients with acute lymphoblastic leukemia (ALL). We describe two childhood cases in which a der(22)t( I ;22)(q21-23;pI 3) cytogene