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Loss of heterozygosity on the short arm of chromosome 3 in nasopharyngeal carcinoma

โœ Scribed by Dolly P. Huang; Kwok-Wai Lo; Peter H.K. Choi; Angela Y.T. Ng; Shiu-Ying Tsao; Gary K.C. Yiu; Joseph C.K. Lee


Book ID
119104819
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
477 KB
Volume
54
Category
Article
ISSN
0165-4608

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## Loss of heterozygosity (LOH) on chromosomes 3p and 9p has been documented in a variety of malignancies, which suggests the presence of tumor suppressor gene loci on these chromosomes. We have studied 77 oral carcinomas for LOH using 16 microsatellite markers distributed over 5 human chromosomes.