✦ LIBER ✦

Loss of heterozygosity on 10q and mutational status of PTEN and BMPR1A in colorectal primary tumours and metastases

✍ Scribed by Karoui, M; Tresallet, C; Julie, C; Zimmermann, U; Staroz, F; Brams, A; Muti, C; Boulard, C; Robreau, A-M; Puy, H

Book ID: 109997993
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 144 KB
Volume: 90
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6601687

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

PTEN/MMAC1 Mutation and Frequent Loss of

PTEN/MMAC1 Mutation and Frequent Loss of Heterozygosity Identified in Chromosome 10q in a Subset of Hepatocellular Carcinomas

✍ Fujiwara, Yoshiyuki ;Hoon, Dave S. B. ;Yamada, Terumasa ;Umeshita, Koji ;Gotoh, 📂 Article 📅 2000 🏛 Wiley (Blackwell Publishing) 🌐 English ⚖ 100 KB

BRCA1 gene mutation and loss of heterozy

BRCA1 gene mutation and loss of heterozygosity on chromosome 17q21 in primary prostate cancer

✍ Toyoaki Uchida; Chunxi Wang; Takefumi Sato; Jiangping Gao; Rikiya Takashima; Aki 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 113 KB 👁 1 views

The tumor suppressor gene BRCA1 on chromosome 17q21 has been characterized and shown to be mutated in patients with familial breast and ovarian cancer. Several studies examined the relatives of women with breast cancer and noted an association with ovarian and prostate cancer. This study investigate

Allelic losses on chromosome arm 10q and

Allelic losses on chromosome arm 10q and mutation of thePTEN(MMAC1) tumour suppressor gene in primary and metastatic malignant melanomas

✍ Julia Reifenberger; Marietta Wolter; J. Boström; Rainer Büschges; Klaus W. Schul 📂 Article 📅 2000 🏛 Springer 🌐 English ⚖ 105 KB

Loss of heterozygosity on chromosome 10q

Loss of heterozygosity on chromosome 10q is associated with earlier onset sporadic colorectal adenocarcinoma

✍ Adeshina S. Fawole; David J. Simpson; Ramesh Rajagopal; Jackie Elder; Tracey A. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 230 KB 👁 2 views

## Abstract Recent studies have shown that loss of heterozygosity (LOH) on chromosome 10q is a frequent event in a number of tumour types including colorectal cancers. Because previous studies have used markers located mainly distally on chromosome 10, we have examined 114 sporadic colorectal adeno

Loss of Heterozygosity and Mutational An

Loss of Heterozygosity and Mutational Analyses of the ACTRII Gene Locus in Human Colorectal Tumors

✍ Olaru, A. 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 761 KB

Frequent loss of heterozygosity for mark

Frequent loss of heterozygosity for markers on chromosome arm 10q in chondrosarcomas

✍ Wendy H. Raskind; Ernest U. Conrad; Mark Matsushita 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 631 KB

Many tumors exhibit loss of heterozygosity (LOH) for polymorphic markers in regions of the genome that contain genes whose normal function can suppress tumor growth. Mapping of regions of LOH can help identify putative tumor suppressor loci that play a role in the pathogenesis of a disease. We evalu