Loss of heterozygosity of thenm23-H1gene in human renal cell carcinomas
✍ Scribed by Maja Herak Bosnar; Krešimir Pavelić; Reno Hrašćan; Žarko Zeljko; Ivan Krhen; Zvonimir Mareković; Šimun Križanac; Jasminka Pavelić
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 377 KB
- Volume
- 123
- Category
- Article
- ISSN
- 1432-1335
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Loss of imprinting (LOI) of the igf 2 and h19 genes has been found not only in embryonal tumors but also in common adult cancers. To determine any possible role of genomic imprinting in the development of renal-cell carcinomas (RCCs), we examined the imprinting status of igf 2 and h19 in a series of
To determine whether a tumor suppressor gene of importance to epithelial ovarian cancer resides on the X chromosome, we examined loss of heterozygosity (LOH) in 123 epithelial ovarian cancer cases. In 54 such cases, we examined LOH at 26 loci on the human X chromosome. In eight cases, we examined LO