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Loss of heterozygosity and protein expression of APC gene in renal cell carcinomas

✍ Scribed by Nives Pećina-Ślaus; Krešimir Pavelić; Jasminka Pavelić


Publisher
Springer
Year
1999
Tongue
English
Weight
132 KB
Volume
77
Category
Article
ISSN
0946-2716

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Loss of imprinting (LOI) of the igf 2 and h19 genes has been found not only in embryonal tumors but also in common adult cancers. To determine any possible role of genomic imprinting in the development of renal-cell carcinomas (RCCs), we examined the imprinting status of igf 2 and h19 in a series of