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Loss of Heterozygosity of Chromosome 3p Sequences Is an Infrequent Event in Endometrial Cancer

โœ Scribed by Martin F. Arlt; Thomas J. Herzog; David G. Mutch; Paul J. Goodfellow

Book ID
115616750
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
71 KB
Volume
60
Category
Article
ISSN
0090-8258

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Loss of heterozygosity from the short arm of chromosome 8 is an early event in breast cancers
โœ M. Lisa Yarernko; Wendy M. Recant; Carol A. Westbrook ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 484 KB

Loss of heterozygosity (LOH) from the short arm of chromosome 8 (8p) is common t o many human carcinomas, including those of the colon and prostate. It localizes to two discrete regions, 8p21 and 8p22. This suggests the presence of at least two tumor suppressor genes (TSGs) on this chromosome arm. H