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Loss of heterozygosity for a chromosome 3 sequence presumably at 3p21 in small cell lung cancer

✍ Scribed by Hans Mooibroek; Jan Osinga; Pieter E. Postmus; Ben Carritt; Charles H.C.M. Buys


Book ID
119103400
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
323 KB
Volume
27
Category
Article
ISSN
0165-4608

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Deletions involving the chromosome 9p21 region have been reported as frequent events in non-small cell lung cancer (NSCLC). To investigate potential tumor-suppressor gene (TSG) loci within the 9p21 region, which also harbors the candidate TSG locus CDKN2a, we studied 32 cases of primary NSCLC for lo