𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Loss of heterozygosity of APC and DCC tumor suppressor genes in human sporadic colon cancer

✍ Scribed by Sanda Šturlan; S. Kapitanović; Duje Kovačević; Josip Lukač; Šime Spaventi; Radan Spaventi; Krešimir Pavelić


Publisher
Springer
Year
1999
Tongue
English
Weight
168 KB
Volume
77
Category
Article
ISSN
0946-2716

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Abnormalities of the RB1 and DCC tumor s
✍ Claire M. Barton; Arthur B. McKie; Annette Hogg; Brita Bia; George Elia; Stewart 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 721 KB

## Abstract Evidence of __RB1__ allele loss was found in only 6% of pancreatic cancers, and we found no significant sequence abnormalities nor loss of RB protein expression in a panel of tumors and cell lines. Using reverse transcription‐polymerase chain reaction and Southern blot analysis, we foun

Relationship between loss of heterozygos
✍ Zhe Piao; Hoguen Kim; Bong Kyun Jeon; Woo Jung Lee; Chanil Park 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB 👁 2 views

## Background: Hepatocellular carcinoma (hcc) is one of the most common human tumors in asia and africa. the molecular genetic changes involving both protooncogenes and tumor suppressor genes are known to be involved in hepatocarcinogenesis, but the roles of the known tumor suppressor genes in hepa

A novel tumor suppressor gene RhoBTB2 (D
✍ Haiting Mao; Xun Qu; Yongmei Yang; Wenshu Zuo; Ye Bi; Chengjun Zhou; Haipeng Yin 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 159 KB 👁 1 views

## Abstract RhoBTB2 was isolated recently as a tumor suppressor gene from human chromosome 8p21.3. Although RhoBTB2 was found to be frequently lost in breast cancer lines, expression status of RhoBTB2 in sporadic breast cancer tissues and its clinical and prognostic value, however, remain unclear.

Hypermethylation of the tumor suppressor
✍ Mei Y. Yu; Joanna H.M. Tong; Paul K.S. Chan; Tin L. Lee; Michael W.Y. Chan; Anth 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 162 KB 👁 1 views

## Abstract Loss of heterozygosity (LOH) at chromosome 3p21 is frequent in cervical cancers. The candidate tumor suppressor gene, __RASSF1A__ located at 3p21.3, is found to be inactivated in several major human cancers, implicating its significance in carcinogenesis. We aimed to investigate the sta