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Loss of heterozygosity in sporadic oesophageal tumors in the tylosis oesophageal cancer (TOC) gene region of chromosome 17q

✍ Scribed by von Brevern, M; Hollstein, M C; Risk, J M; Garde, J; Bennett, W P; Harris, C C; Muehlbauer, K-R; Field, J K


Book ID
110061617
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
382 KB
Volume
17
Category
Article
ISSN
0950-9232

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The tumor suppressor gene BRCA1 on chromosome 17q21 has been characterized and shown to be mutated in patients with familial breast and ovarian cancer. Several studies examined the relatives of women with breast cancer and noted an association with ovarian and prostate cancer. This study investigate