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Loss of heterozygosity in clonal evolution with genetic progression and divergence in spindle cell carcinoma of the gallbladder

โœ Scribed by Atsushi Arakawa; Hiroaki Fujii; Toshiharu Matsumoto; Shu Hirai; Koichi Suda


Book ID
116533668
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
541 KB
Volume
35
Category
Article
ISSN
1532-8392

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Loss of heterozygosity studies in squamo
โœ David T. Ransom; J. Helen Leonard; John H. Kearsley; Gavin R. Turbett; Kathy Hee ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 800 KB

Background. Loss of heterozygosity (LOH) studies have been pivotal in identifying tumor suppressor genes involved in the pathogenesis of a number of cancers. In squamous cell carcinomas of the head and neck region (SCCHN), LOH studies using the Southern blot technique are scarce. Methods. SCCHNs we