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Loss of FHIT gene expression in pancreatic carcinoma cells

✍ Scribed by Simon, S.B.; Bartsch, D.; Barth, P.; Prasnika, N.; Arnold, R.; Göke, B.


Book ID
122982638
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
179 KB
Volume
114
Category
Article
ISSN
0016-5085

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Chromosomal aberrations and inactivation of tumour suppressor genes are frequent in acute leukaemia. To determine whether the FHIT gene is involved in the development of leukaemia, we examined the FHIT transcript in 65 leukaemia cell lines, 5 fresh acute leukaemia patients at diagnosis and in comple