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Loss of chromosome 10 in glioblastoma: Relation to proliferation and angiogenesis

✍ Scribed by Hidehisa Horiguchi; Takanori Hirose; Toshiaki Sano; Shinji Nagahiro


Book ID
114430901
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
56 KB
Volume
49
Category
Article
ISSN
1320-5463

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Gene deletion of chromosome 10 in 11 tumor tissues removed from nine patients with malignant glioma (seven glioblastomas and two malignant astrocytomas) was investigated. Loss of heterozygosity was found in four of the seven (57%) cases with glioblastoma, whereas heterozygosity was preserved in two