Longitudinal study of islet cell antibody class and development of diabetes in the NOD mouse
β Scribed by Reddy, S.; Bibby, N.J.; Elliott, R.B.
- Book ID
- 122978298
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 86 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0896-8411
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π SIMILAR VOLUMES
IgG and IgM class insulin autoantibodies were measured by an enzyme-linked immunosorbent assay in sera from members of the Barts-Windsor-Middlesex prospective family study for Type I (insulin-dependent) diabetes. One hundred and twelve individuals from 28 families were selected for study on the basi
The nonobese diabetic (NOD) mouse spontaneously develops an autoimmune diabetes that shares many immunogenetic features with human insulin-dependent diabetes mellitus (IDDM), type 1 diabetes. The mononuclear cell infiltrates in the islet, which results in the development of insulitis (a prerequisite