Longitudinal and Transverse 1 H− 15 N Dipolar/ 15 N Chemical Shift Anisotropy Relaxation Interference: Unambiguous Determination of Rotational Diffusion Tensors and Chemical Exchange Effects in Biological Macromolecules
✍ Scribed by Kroenke, Christopher D.; Loria, J. Patrick; Lee, Larry K.; Rance, Mark; Palmer, Arthur G.
- Book ID
- 121198383
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 143 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0002-7863
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## Abstract We describe direct methods for the measurement of the transverse and longitudinal ^15^N chemical shift anisotropy–dipolar cross‐correlation rates based on comparison of the ^15^N doublet components observed in ^1^H‐coupled ^1^H–^15^N HSQC‐type spectra. This allows the determination of t
We demonstrate a dipolar-chemical shift correlation technique for sign-sensitive determination of the torsion angle in solid peptides and proteins under magic-angle spinning. The indirect dimension of the experiment is obtained by separate but synchronous evolution of the magnetization under the 15