A retinal pigment epithelial (RPE) cell line (K-1034) was examined for its susceptibility to human herpesvirus 6 variant A (HHV-6A). Exposure of K-1034 cells to HHV-6A induced the formation of multinucleated giant cells, which was suppressed by an inhibitor of viral DNA synthesis. In the giant cells
Long-term productive human cytomegalovirus infection of a human neuroblastoma cell line
✍ Scribed by Jindrich Cinatl Jr.; Jens-U. Vogel; Jaroslav Cinatl; Bernard Weber; Holger Rabenau; Milos Novak; Bernhard Kornhuber; Hans-W. Doerr
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- French
- Weight
- 998 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
✦ Synopsis
Human neuroblastoma cell line UKF-NB-4 persistently infected with human cytomegalovirus (HCMV) strain AD I69 was established to study the effects of long-term HCMV infection on virus production and phenotypic characteristics of tumour cells.
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