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Enhancement of human rotavirus infectivity in a monkey kidney cell line by human expressed breast milk

✍ Scribed by Barbara M. Totterdell; J. Macleod; I.L. Chrystie; J.E. Banatvala

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
277 KB
Volume
9
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

Eight of forty (20%) human expressed breast milks enhanced the infectivity of human rotavirus (HRV) when assayed by immunofluorescence in a monkey kidney cell line (LLC‐MK~2~). This enhancement was demonstrated with two HRV strains, one derived from a fecal specimen of a child with acute gastroenteritis, the other a tissue culture adapted strain. The phenomenon could have important implications in the pathogenesis of HRV infections and in future vaccine programs.

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