Long-term evolution of chronic hepatitis B in children with antibody to hepatitis B e antigen
β Scribed by F. Bortolotti; R. Calzia; P. Cadrobbi; C. Crivellaro; A. Alberti; M.G. Marazzi
- Book ID
- 117163016
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 378 KB
- Volume
- 116
- Category
- Article
- ISSN
- 1097-6833
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Data regarding the outcome of children with chronic hepatitis B after seroconversion are scarce. We describe the long-term evolution of these patients. One hundred and three children with antibody against hepatitis B e antigen and normal alanine aminotransferase (ALT) levels were followed for 0.6 to
A commercial radioimmunoassay was adapted to detect serum Dane particle-associated HBeAg in patients whose sera contained the homologous antibody. HBeAg was released from Dane particles with guanidine HC1. Dane particles were separated from anti-HBe by gel-filtration (Sepharose 4B) and ultracentrif