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Long-arm deletions in chromosome 6 in acute myelogenous leukemia: update on two cases

✍ Scribed by T.S. Sundareshan; V. Lakshmi Devi; D.S. Madhumathi; L. Appaji; M.H. Girish; Kumar Prabhash; P.P. Bapsy


Book ID
113512413
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
156 KB
Volume
154
Category
Article
ISSN
0165-4608

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We have characterised a region of deletion on the long arm of chromosome 6 (6q) in six cases of acute lymphobiastic leukaemia, by fluorescence in situ hybridisation, using a series of YAC clones which map to 6q. Conventional cytogenetic analysis of four of these cases had been interpreted as showing