𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Locus of the inhibition of protein synthesis by aldo-ketones

✍ Scribed by Haruki Otsuka; Laszlo G. Együd

Publisher
Elsevier Science
Year
1968
Tongue
English
Weight
252 KB
Volume
2
Category
Article
ISSN
0303-2647

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibition of Protein Synthesis by RA-VI
Inhibition of Protein Synthesis by RA-VII
✍ B.V. Sirdeshpande; P.L. Toogood 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 476 KB

The antitumor natural product RA-VII has been evaluated as an inhibitor of protein synthesis in vitro. Complete inhibition of protein synthesis in rabbit reticulocyte lysates is observed with \(5 \mu \mathrm{m}\) RA-VII. Mechanistic studies using purified elongation factors and ribosomes identify RA

Reversible inhibition of RNA synthesis a
Reversible inhibition of RNA synthesis and irreversible inhibition of protein synthesis by D-galactosamine in isolated mouse hepatocytes
✍ J. Mandl; K. Mészáros; F. Antoni; Z. Spolarics; T. Garzó 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 374 KB

The inhibition of RNA synthesis of isolated mouse liver parenchymal cells caused by 10 mM D-galactosamine was reversible, while the inhibition of protein synthesis remained unaltered after the removal of galactosamine. 10(-5)M epinephrine and 10(07)M glucagon have been shown to decrease aminoglycoge

Synthesis of peptide fluoromethyl ketone
Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B
✍ David Rasnick 📂 Article 📅 1985 🏛 Elsevier Science 🌐 English ⚖ 432 KB

Peptide fluoromethyl ketones have been synthesized for the first time. The inhibitor 3-(Nbenzyloxycarbonylphenylalanylamido)-DL-l-fluoro-2-butanone (Z-Phe-AlaCHZF) was found to be a 30-fold more potent inactivator of human cathepsin B than 3-(N-benzyloxycarbonylphenylalanylamido)~L-I-diazo-2-butanon