Female (I/St x C57BL/St)F~ mice heterozygous at the sex-linked phosphoryIase kinase deficiency locus (Phk) have phosphorylase kinase activities averaging 860/00 that of mice homozygous for the wild-type allele (C57BL/St), i.e., 72%o greater than the sum of one-half the activities of the parental str
Location of phosphorylase kinase (Phk) in the mouse X chromosome
β Scribed by Frans Huijing; Eva M. Eicher; Douglas L. Coleman
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 213 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0006-2928
No coin nor oath required. For personal study only.
β¦ Synopsis
The phosphorylase kinase deficiency (Phk) locus has been located in the mouse X chromosome, the order of genes being centromere-Bn-Phk-Ta-jp. Since the Phk locus of the mouse may be identical to the locus responsible for the X-linked phosphorylase kinase deficiency trait of man, and there may be a high degree of gene-order homology in the X chromosome of all mammals, the location of Phk in the mouse reported here may aid in locating the phosphorylase kinase gene on the X chromosome of man.
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