## Abstract Mammals possess two genetically distinct forms of phosphoglycerate kinase (PGK). Only the Xβlinked PGKβA isozyme is detectable by electrophoresis of somatic and ovarian tissues of the mouse and of most other eutherian mammals studied to date. The PGKβB isozyme is highly active in testes
X linkage of phosphoglycerate kinase in the mouse
β Scribed by Leslie P. Kozak; Gordon K. McLean; Eva M. Eicher
- Publisher
- Springer
- Year
- 1974
- Tongue
- English
- Weight
- 387 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0006-2928
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In a family with an extremely rare PGK variant, linkage with Xg was investigated. The analysis suggested that linkage might prove measurable. The estimate of the recombination fraction was 0.07 and the 90% probability limits were 0.05--0.28. The height of the antilog curve was 19.
Using a human phosphoglycerate kinase (PGK) cDNA probe, we have identified a common Pst I restriction site polymorphism on the human X chromosome in all ethnic groups studied. The polymorphic Pst I site was absent in 40.4% of 94 X chromosomes of unrelated subjects. Heterozygous females can only be d
## Abstract Addition of EDTA to the medium significantly enhances mouse embryo development in culture. Embryos cultured in the absence of EDTA exhibit abnormal increases in glycolytic activity that result in reduced development. Culture with EDTA was able to prevent this increase in glycolysis and,