Localization of lactate dehydrogenase activity in the cells of the fish (Xiphophorus helleri) eye
✍ Scribed by Whitt, Gregory S. ;Booth, Gary M.
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 1000 KB
- Volume
- 174
- Category
- Article
- ISSN
- 0022-104X
No coin nor oath required. For personal study only.
✦ Synopsis
The swordtail (Xiphophorus helleri) eye contains the Ad and B4 isozymes of lactate dehydrogenase (LDH) as do all vertebrates and in addition contains a distinctive lactate dehydrogenase, the Eq isozyme, found only in fish. LDH in the fish eye is located predominantly in the neural retina, especially in the inner segments of the photoreceptor cells. This neural retinal LDH activity consists mainly of the B4 and Eq isozymes which are more resistant than the Aq isozyme to inhibition by 1.8 M urea. The sclera, cornea, and lens possess mainly the urea-sensitive A4 isozyme. The specific cellular location of the Eq isozyme suggests that it plays a role in the bicchemistry of vision.
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