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Localization of functional calcitonin gene-related peptide binding sites in a subpopulation of cultured dorsal root ganglion neurons

✍ Scribed by G Segond von Banchet; A Pastor; C Biskup; C Schlegel; K Benndorf; H.-G Schaible

Book ID: 117490363
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 945 KB
Volume: 110
Category: Article
ISSN: 0306-4522
DOI: 10.1016/s0306-4522(01)00547-4

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## Abstract Calcitonin gene‐related peptide (CGRP) is synthesized in dorsal root ganglion (DRG) neurons and released from primary afferent neurons to mediate hemodynamic effects and neurogenic inflammation. The effect of the proinflammatory cytokine interleukin‐1 (IL‐1)‐β on CGRP release from these