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Inflammatory mediators release calcitonin gene-related peptide from dorsal root ganglion neurons of the rat

✍ Scribed by B. Averbeck; I. Izydorczyk; M. Kress


Book ID
117489668
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
352 KB
Volume
98
Category
Article
ISSN
0306-4522

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## Abstract Calcitonin gene‐related peptide (CGRP) is synthesized in dorsal root ganglion (DRG) neurons and released from primary afferent neurons to mediate hemodynamic effects and neurogenic inflammation. The effect of the proinflammatory cytokine interleukin‐1 (IL‐1)‐β on CGRP release from these