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Localization and Significance of Urokinase Plasminogen Activator and its Receptor in Placental Tissue from Intrauterine, Ectopic and Molar Pregnancies

✍ Scribed by C Floridon; O Nielsen; B Hølund; L Sunde; J.G Westergaard; S.G Thomsen; B Teisner

Book ID
114477778
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
407 KB
Volume
20
Category
Article
ISSN
0143-4004

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The urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play an important role in tumour invasion. Previous studies have shown by RT-PCR that uPA and uPAR mRNAs are expressed in human hepatocellular carcinoma (HCC). Here, in situ hybridization, immunohistochemistry, and double immuno¯