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Liver transplantation and new therapeutic approaches for familial amyloidotic polyneuropathy (FAP)

✍ Scribed by Yukio Ando

Publisher
Springer
Year
2005
Tongue
English
Weight
582 KB
Volume
38
Category
Article
ISSN
0918-4287

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Liver transplantation (LTx) for familial amyloidotic polyneuropathy (FAP) is an accepted treatment for this fatal disease. However, the long-term outcome with respect to that of nontransplanted patients has not been fully elucidated. The aim of this study was to compare the long-term survival of Swe

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Familial amyloidotic polyneuropathy is an inherited form of amyloidosis associated with a mutant form of a protein called transthyretin. The Methionine-30 variant is the most frequent mutation observed. This disorder is caused by deposition of this protein as amyloid in several organs, such as the h