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Liver-microsome-mediated formation of alkylating agents from vinyl bromide and vinyl chloride

✍ Scribed by A. Barbin; H. Brésil; A. Croisy; P. Jacquignon; C. Malaveille; R. Montesano; H. Bartsch

Book ID
118310416
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
462 KB
Volume
67
Category
Article
ISSN
0006-291X

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Human, rat and mouse liver-mediated muta
Human, rat and mouse liver-mediated mutagenicity of vinyl chloride in S. typhimurium strains
✍ H. Bartsch; C. Malaveille; R. Montesano 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 641 KB

## Abstract Exposure of S. typhimurium strains TA 1530, TA 1535 and G‐46 to vinyl chloride increased the number of His^+^ revertants/plate 16, 12 or 5 times over the spontaneous mutation rate. After 6 h of exposure to vinyl chloride, the mutagenic response for TA 1530 strain was enhanced 7‐, 4‐ or