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Liquid-Phase Synthesis of Mixture-Based Bicyclic β-Lactam Libraries.

✍ Scribed by Szilvia Gedey; Pirjo Vainiotalo; Istvan Zupko; Peter A. M. de Witte; Ferenc Fueloep

Publisher
John Wiley and Sons
Year
2004
Weight
81 KB
Volume
35
Category
Article
ISSN
0931-7597

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Liquid-phase synthesis of mixture-based
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## Abstract Five sets of 27‐membered combinatorial libraries of alicyclic β‐lactams were prepared __via__ liquid‐phase Ugi 4‐center 3‐component reactions (U‐4C‐3CR) utilizing 3 different __cis__ β‐amino acids, 3 different isonitriles and 5×3 sets of aldehydes. Through combinations of the building b

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