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Liquid-Phase Combinatorial Synthesis of Alicyclic β-Lactams via Ugi Four-Component Reaction.

✍ Scribed by Szilvia Gedey; Johan Van der Eycken; Ferenc Fueloep


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of Small
✍ G. C. B. HARRIMAN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

Synthesis of Small and Medium Sized 2,2-Disubstituted Lactams via the " Intramolecular" Three Component Ugi Reaction. -Tethered keto-acids undergo an intramolecular three-component Ugi reaction with a variety of primary amines and isocyanates to form five-to eight-membered lactams in good yields. -(